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SCIENCE NEWS
Researcher's Discovery Points to a New Treatment Avenue for Acute Myeloid Leukemia
A multinational team has developed the first leukemia therapy that targets a protein, CD123, on the surface of cancer stem cells that drive acute myeloid leukemia (AML), which is an aggressive disease with a poor outcome. [Princess Margaret Hospital, Ontario Cancer Institute, Toronto]
Human Sperm Created From Embryonic Stem Cells
Human sperm have been created using embryonic stem cells for the first time in a scientific development which will lead researchers to a better understanding of the causes of infertility. [Newcastle University, Institute of Human Genetics, Newcastle]
First Human Receives Cardiac Stem Cells in Clinical Trial to Heal Damage Caused by Heart Attacks
Doctors announced the completion of the first procedure in which a patient's own heart tissue was used to grow specialized heart stem cells that were then injected back into the patient's heart to repair and re-grow healthy muscle. [Cedars-Sinai Heart Institute, Los Angeles]
Human Cardiac Master Stem Cells Identified
Researchers have identified the earliest master human heart stem cell from human embryonic stem cells - ISL1+ progenitors - that give rise to a family of cells that form the essential portions of the human heart.
[Harvard University, Harvard Stem Cell Institute, Boston]
Blood Stem Cell Growth Factor Reverses Memory Decline in Alzheimer's Mice
A human growth factor that stimulates blood stem cells to proliferate in the bone marrow reverses memory impairment in mice genetically altered to develop Alzheimer's disease. [University of South Florida and James A. Haley Hospital, Tampa]
Researchers Discover that Phenoxodiol Kills Rapidly Proliferating T-Cells
Researchers have found that abnormally proliferating human T-cells, rapidly dividing cancer cells such as primary myeloid and lymphoid leukemic blast cells undergo programmed cell death when exposed briefly to the investigational anti-tumor drug phenoxodiol. [Malaghan Institute of Medical Research, Wellington]
Stem Cells Show Size-Specific Reaction to Nanopatterns
Scientists in Germany have found that surface topography can be more important than chemistry for stem cells. [University of Erlangen-Nürnberg, Nuremberg]
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