Connexon Creative - Cord Blood News 1.05

In this issue: Science News | Current Publications | Industry News | Policy News | Events

TOP STORIES

Study Reveals Major Genetic Differences between Blood and Tissue Cells
Important questions raised about genetic research based only on blood samples; new treatment in vascular disease foreseen at the same time. [McGill University, Montreal]

SCIENCE NEWS

Complimentary Wallchart: Guide to Hematopoietic Colonies Derived from Human Cord Blood Progenitors
Request your copy

Endothelial Cells in Blood May Help Spread Childhood Cancer
Endothelial cells and progenitor cells circulating in the blood of pediatric cancer patients may play a role in the inception and progression of metastatic disease. [University of Paris-Sud, Orsay]

Induced Pluripotent Stem Cells Repair Heart, Mayo Clinic Study Shows
Researchers reprogrammed ordinary fibroblasts and converted them into stem cells that fix heart damage caused by infarction. [Mayo Clinic, Rochester]

New Technology For Improved Scientific Results
New technology that identifies and removes dead and dying cells from cell populations grown in laboratories is now available to UK scientists. [ImmunoSolv Ltd., Edinburgh]

CURRENT PUBLICATIONS

Donor, Recipient, and Transplant Characteristics As Risk Factors After Unrelated Donor PBSC Transplantation: Beneficial Effects of Higher CD34+ Cell Dose
Higher CD34+ cell doses resulted in more rapid engraftment, less transplant-related mortality, and better 3-year overall survival, but did not increase the risk of GVHD. [Blood]

Evaluation of NIH Consensus Criteria For Classification of Late Acute and Chronic GVHD
Results support the consensus recommendation that, with appropriate stratification, clinical trials can include patients with late acute GVHD as well as those with NIH chronic GVHD. [Blood]

A Meta-analysis of Patients Receiving Allogeneic or Autologous Hematopoietic Stem Cell Transplant in Mycosis Fungoides and Sézary Syndrome
This study supports the belief that allogeneic stem cell transplant offers a better survival and disease-free outcome versus autologous stem cell transplant in MF/Sézary syndrome, likely because of a graft-versus-lymphoma effect. [Biol Blood Marrow Transplant]

Successful Treatment of Severe Acute Intestinal Graft-versus-Host Resistant to Systemic and Topical Steroids with Alemtuzumab
These data suggest that treatment with alemtuzumab has favorable activity in severe intestinal GVHD after allogeneic HCT, but emphasize the importance of careful monitoring and anti-infectious supportive care. [Biol Blood Marrow Transplant]

Revealing Tumor Immunity After Hematopoietic Stem Cell Transplantation
New studies show that tumor-reactive T cells are directed against diverse tumor-specific targets as well as minor histocompatibility antigens. [Clin Cancer Res]

Clinical Significance of Serum Hepcidin Levels on Early Infectious Complications in Allogeneic Hematopoietic Stem Cell Transplantation
These results suggest that the pretransplant serum hepcidin-25 level may be a useful marker for predicting the risk of early bacterial complications after allogeneic hematopoietic stem cell transplantation. [Biol Blood Marrow Transplant]

Lack of Prompt Expansion of Cytomegalovirus pp65 and IE-1-Specific IFN-gamma CD8+ and CD4+ T Cells is Associated With Rising Levels of pp65 Antigenemia and DNAemia During Pre-emptive Therapy in Allogeneic Hematopoietic Stem Cell Transplant Recipients
Lack of prompt expansion of CMV pp65 and IE-1-specific IFN-gamma CD8+ and CD4+ T cells is associated with rising levels in antigenemia and DNAemia during pre-emptive therapy. [Bone Marrow Transplant]

INDUSTRY NEWS

Blood Centers Merge
Lakeland-based BloodNet USA and Florida Blood Services join forces; no layoffs are expected, officials say.

Blood Supply at Risk
The Central Illinois Community Blood Center has expressed concern that the state's plan to reduce its work force by more than 2,000 employees will seriously affect blood supply.

UF Lands $26M NIH Grant
The University of Florida is getting nearly $26 million over five years for an effort intended to shorten the lag time between the discovery of medical treatments and their widespread use.

Events

2nd TERMIS World Congress In Conjunction With 2009 Seoul Stem Cell Symposium
August 31-September 3, 2009
Seoul, South Korea

XXXVI Annual meeting European Society for Artificial Organs 2009
September 2-5, 2009
Compiègne, France

16th International Society of Developmental Biologists Congress
September 6-10, 2009
Edinburgh, United Kingdom

International Society for Hematology and Stem Cells 38th Annual Scientific Meeting
September 9-12, 2009
Athens, Greece

Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.

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