CURRENT PUBLICATIONS

In Vivo Prostaglandin E2 Treatment Alters the Bone Marrow Microenvironment and Preferentially Expands Short-Term Hematopoietic Stem Cells
In vivo PGE2 treatment, likely through a combination of direct and microenvironmental actions, preferentially expands ST-HSCs in the absence of marrow injury, with no negative impact on hematopoietic progenitors or Long Term-HSCs. [Blood]

Allogeneic Hematopoietic Stem Cell Transplantation in Children and Adolescents with Recurrent and Refractory Hodgkin Lymphoma: An Analysis of the European Group for Blood and Marrow Transplantation
Children and adolescents with recurring Hodgkin lymphoma show reasonable results with allogeneic hematopoietic stem cell transplantation. Especially patients allografted in recent years with good performance status and chemosensitive disease show highly encouraging results. [Blood]

Administration of Short-Term Immunosuppressive Agents after DLI Reduces the Incidence of DLI-Associated Acute GVHD without Influencing the GVL Effect
Using immunosuppressive agents for 2-4 weeks may reduce Donor lymphocyte infusion (DLI)-associated acute GVHD without influencing relapse and survival after G-CSF-primed DLI. [Bone Marrow Transplant]

Differentiation of Mesenchymal Stromal Cells Derived from Umbilical Cord Wharton's Jelly into Hepatocyte-Like Cells
Umbilical Cord MSC can differentiate into functional hepatocyte-like cells following the induction of hepatotic growth factor (HGF) and fibroblast growth factor-4 (FGF-4). UC MSC can serve as a favorable cell source for tissue engineering in the treatment of liver disease. [Cytotherapy]

Therapeutic Benefit of Human Umbilical Cord Derived Mesenchymal Stromal Cells in Intracerebral Hemorrhage Rat: Implications of Anti-inflammation and Angiogenesis
Intracerebral administration of UC-MSC could accelerate neurological function recovery of intracerebral hemorrhage rat, the underlying mechanism may ascribe to their ability to inhibit inflammation and promote angiogenesis. [Cell Physiol Biochem]

POLICY NEWS

Safety Call Over Stem Cell Trips
A clampdown on unproven and potentially unsafe stem cell research is being called for by an expert group.

FOOD AND DRUG ADMINISTRATION (United States)

FDA Study Indicates Most Industry Postmarketing Studies Meet Timelines
Makers of approved drugs and biologics generally are meeting their regulatory obligations and complete their postmarketing studies in a timely manner, according to a recent study.

NATIONAL INSTITUTES OF HEALTH (United States)

Clarification of NOT-OD-08-014 Regarding Obtaining Assistance from NIH for Registration and Reporting of Results in ClinicalTrials.gov (NOT-OD-09-147)

Enhancing Peer Review: The NIMH Announces Consolidation of Review Criteria for NIMH Career Opportunities in Research (COR) Honors Undergraduate Research Training Grant (T34) Submitted for FY 2010 Funding (NOT-MH-09-018)

EVENTS

51st ASH Annual Meeting and Exposition
December 9-12, 2009
New Orleans, LA

2010 BMT Tandem Meetings
February 24-28, 2010
Orlando, Florida

The European Group for Blood & Marrow Transplantation Annual Meeting
March 21-24, 2010
Vienna, Austria

Canadian Blood and Marrow Transplant Consortium Annual Meeting
April 7-10, 2010
Vancouver, BC

16th Annual International Society for Cellular Therapy Meeting
May 22-26, 2010
Philadelphia, Pennsylvania

Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.

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