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TOP STORIES

Private Umbilical Cord Banking Not Cost-Effective, UCSF Research Shows
Private cord blood banking is not cost-effective because it costs an additional $1,374,246 per life-year gained, according to a new analysis by UCSF researchers. [The University of California, San Francisco]

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SCIENCE NEWS

Rare Genetic Disease Successfully Reversed Using Stem Cell Transplantation
In a recent study, the rare genetic disorder, cystinosis in mice were corrected with stem cell transplantation. [Scripps Research Institute, La Jolla]

Stale Blood can Double Death Rate
Researchers found that patients requiring a major transfusion were twice as likely to die if they received red blood cells stored for a month or longer. [Hartford Hospital, Connecticut]

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CURRENT PUBLICATIONS

Guidelines for Preventing Infectious Complications among Hematopoietic Cell Transplantation Recipients: A Global Perspective
This report represents an update of the guidelines published in 2000 for preventing infections among hematopoietic cell transplantion (HCT) recipients [Blood]

Higher Infused CD34+ Hematopoietic Stem Cell Dose Correlates with Earlier Lymphocyte Recovery and Better Clinical Outcome after Autologous Stem Cell Transplantation in Non-Hodgkin's Lymphoma
Lymphocyte recovery after autologous stem cell transplantation has been shown to be associated with positive clinical outcome in non-Hodgkin's lymphoma, and this study sought to identify variables that affect lymphocyte recovery and survival after ASCT. [Transfusion]

Successful Treatment of the Murine Model of Cystinosis Using Bone Marrow Cell Transplantation
Using the murine model for cystinosis, Ctns-/- mice, researchers performed syngeneic bone marrow cell, hematopoietic stem cell, and mesenchymal stem cell transplantation. [Blood]

Therapeutic Benefit of Human Umbilical Cord Derived Mesenchymal Stromal Cells in Intracerebral Hemorrhage Rat: Implications of Anti-inflammation and Angiogenesis
Results demonstrated that UC-MSC treatment significantly improved neurological function deficits and decreased injury volume of ICH rats. [Cell Physiol Biochem]

Cord Blood Transplantation from Unrelated Donors in Adults with High-Risk Acute Myeloid Leukemia
CBT from unrelated donors is a curative treatment for a substantial number of patients with high-risk AML, particularly if transplant is performed with highly cellular units in patients in first CR. [Biol Blood Marrow Transplant]

Drug Interaction Between Voriconazole and Calcineurin Inhibitors in Allogeneic Hematopoietic Stem Cell Transplant Recipients
Although voriconazole has been shown to interact with calcineurin inhibitors, this interaction has not been thoroughly examined. [Bone Marrow Transplant]

Antiviral Responses following LLME-Treated Lymphocyte Infusions: Graft-versus-Infection Without Graft-versus-Host Disease
This paper examines the pace of immune recovery and the rapid development of antiviral responses in 6 patients who developed viral infections during the time period immediately preceding or coincident with the administration of the L-leucyl-L-leucine methyl ester donor lymphocyte infusion. [Biol Blood Marrow Transplant]

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INDUSTRY NEWS

Cleveland BioLabs and Zhejiang Hisun Pharmaceutical Enter License Agreement for Protectan CBLB612 Hematopoietic Stem Cell Stimulator and Mobilizer in China
Cleveland BioLabs Inc., and Zhejiang Hisun Pharmaceutical Co. Ltd. today announced the execution of a license agreement granting Hisun exclusive rights to develop and commercialize Protectan CBLB612 in the People's Republic of China.



POLICY NEWS

Elaine Fuchs to Receive National Medal of Science
President Barack Obama announced today that Elaine Fuchs will receive the National Medal of Science for contributions to the biological sciences.

Californian Stem Cell Agency, Germany Ink Partnership
California's stem cell research funding agency and the German Federal Ministry of Education and Research signed an agreement Thursday that lays the foundation for joint research projects.

Revenue Seen Not Adding Up to Fees
A health-care-overhaul plan from Sen. Max Baucus would assess $123 billion in fees on health insurers, drug and medical-device manufacturers, and medical labs.

NATIONAL INSTITUTES OF HEALTH (United States)

NIH Opens Website for Human Embryonic Stem Cell Lines for Approval and Announces Members of Working Group
The NIH is now accepting requests for human embryonic stem cell (hESC) lines to be approved for use in NIH-funded research. The NIH is also pleased to announce the members of a new working group of the Advisory Committee to the Director (ACD): the Working Group for Human Embryonic Stem Cell Eligibility Review.

FOOD AND DRUG ADMINISTRATION (United States)

2009 Biological License Application Approvals

Submission of Quality Information for Biotechnology Products in the Office of Biotechnology Products: Extension of Deadlines to Request Participation in Pilot Program and to Submit Applications, etc., 47806-47807 [E9-22378]

Preparation for International Conference on Harmonization; Public Meeting, 47948-47949 [E9-22445]




EVENTS

51st ASH Annual Meeting and Exposition
December 9-12, 2009
New Orleans, LA

2010 BMT Tandem Meetings
February 24-28, 2010
Orlando, Florida

The European Group for Blood & Marrow Transplantation Annual Meeting
March 21-24, 2010
Vienna, Austria

Canadian Blood and Marrow Transplant Consortium Annual Meeting
April 7-10, 2010
Vancouver, BC

16th Annual International Society for Cellular Therapy Meeting
May 22-26, 2010
Philadelphia, Pennsylvania

Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.


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