ABSTRACTS

ES-Cell Derived Hematopoietic Cells Induce Transplantation Tolerance The researcher's data show, for the first time, the efficacy of ES-derived CD45+ HPCs to engraft in allogenic recipients without the use of immunosuppressive agents, there by protecting cardiac allografts from rejection.
Kinetic Analysis of Neurotrophin-3-Mediated Differentiation of Embryonic Stem Cells into Neurons The goal of this study was to develop a kinetic analysis that could predict the behavior of embryonic stem cell-derived neural progenitor cells (ESNPCs) in response to treatment with neurotrophin-3 (NT-3).
Cell-Extracellular Matrix Interactions Regulate Neural Differentiation of Human Embryonic Stem Cells The researchers defined laminin as a key ECM molecule to enhance neural progenitor generation, expansion and differentiation into neurons from hESCs.
Secreted Proteoglycans Directly Mediate Human Embryonic Stem Cell-FGF2 Interactions Critical for Proliferation This paper demonstrates that HSPG are key signaling cofactors in CM-based human ES cell culture.
Isolation of Primordial Germ Cells from Differentiating Human Embryonic Stem Cells In this study, a robust protocol is presented to differentiate two human embryonic stem cell lines (H9 and hES-NCL1) that maximises the numbers of primordial germ cells that may be obtained using a simple FACS strategy for their isolation.
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