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Study Unlocks Stem Cell, DNA Secrets to Speed Therapies
Florida State University researchers have discovered that as embryonic stem cells turn into different cell types, there are dramatic corresponding changes to the order in which DNA is replicated and reorganized.




SCIENCE

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Scientists Trigger Cancer-like Response from Embryonic Stem Cells
Scientists from The Forsyth Institute, working with collaborators at Tufts and Tuebingen Universities, have discovered a new control over embryonic stem cells' behavior.

A Link Between Mitochondria and Tumor Formation in Stem Cells
Researchers report on a previously unknown relationship between stem cell potency and the metabolic rate of their mitochondria.




ABSTRACTS

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Anterior Definitive Endoderm from ESCs Reveals a Role for FGF Signaling
The researchers' findings in defined monolayer differentiation suggest FGF signaling is an important regulator of early anterior mesendoderm differentiation rather than merely a mediator of morphogenetic movement.

Cells Derived from Human Umbilical Cord Blood Support the Long-Term Growth of Undifferentiated Human Embryonic Stem Cells
This study reports the successful culture of two hESC lines (H1 and H9) on human umbilical cord blood-derived fibroblast-like cells.

Skeletal Muscle Differentiation of Embryonic Mesoangioblasts Requires Pax3 Activity
The researchers' data demonstrate that Pax3 is required for the differentiation of mesoangioblast stem cells into skeletal muscle, in keeping with its role in orchestrating entry into the myogenic program.

A Novel Approach for the Derivation of Putative Primordial Germ Cells and Sertoli Cells from Human Embryonic Stem Cells
Using human embryonic stem cells, the researchers describe a novel method for the rapid derivation and enrichment of cells that are comparable to primordial germ cells and Sertoli cells.

A Feeder-Free and Efficient Production of Functional Neutrophils from Human Embryonic Stem Cells
A novel, feeder-free hematopoietic differentiation protocol was established for highly efficient production of neutrophils from human embryonic stem cells.

The Differentiation of Hepatocyte-Like Cells from Monkey Embryonic Stem Cells
This paper's results suggest that by using a specific, empirically determined, culture condition, we were able to direct monkey embryonic stem cells toward a hepatocyte lineage.




INDUSTRY

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University of Georgia Receives $8.3 Million NIH Grant to Study Stem Cells, Cancer
The National Institutes of Health has awarded the University of Georgia a five-year, $8.3 million grant to further its research into the role cell-surface sugars known as glycans play in the development of stem cells and cancer cells.

Lokey Gives $75 Million to Create Nation's Largest Stem Cell Research Center at Stanford
Lorry I. Lokey, the Business Wire founder and philanthropist, is giving $75 million to the Stanford University School of Medicine to help build what is expected to be the nation's largest center for stem cell research.




POLICY

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From Embryo or From Blood Cells: Obama and McCain's Stem Cell Showdown
Do either candidate's record support their stance on stem cell research?



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