In this issue:  Science   |  Abstracts  |  Industry News   |  Policy Subscribe   |   Unsubscribe    TOP STORIES Scientists Shed Light on Inner Workings of Human Embryonic Stem Cells Scientists at UC Santa Barbara show that a microRNA lowers the activity of three key ingredients in the recipe for embryonic stem cells. SCIENCE Gladstone Scientists Identify Key Factors in Heart Cell Creation Scientists at the Gladstone Institute of Cardiovascular Disease have identified for the first time key genetic factors that drive the process of generating new heart cells. Stem Cells Are Going Green to Study Autism A research team led by The Hospital for Sick Children has developed a method to efficiently identify human stem cells by turning them fluorescent green. TriMark Point of Care Testing Conference 2009 May 11, 2009  |  San Diego, California Enter "CONNEXON" at checkout and receive 10% off registration. Visit here to register today. Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community. ABSTRACTS Efficient Mouse Transgenesis Using Gateway-compatible ROSA26 Locus Targeting Vectors and F1 Hybrid ES Cells This study reports the generation of Cre/loxP conditional ROSA26-targeted ES cells within 3-4 weeks by using Gateway(R) cloning to build the target vectors. Dynamic 3D Culture Promotes Spontaneous Embryonic Stem Cell Differentiation in Vitro Spontaneous in vitro differentiation of mouse embryonic stem cells is promoted by a dynamic, three-dimensional, tissue-density perfusion technique with continuous media perfusion and -exchange in a novel four-compartment, interwoven capillary bioreactor. Neuropilin-1 Identifies Endothelial Precursors in Human and Murine Embryonic Stem Cells Before CD34 Expression This study reports that expression of the VEGF co-receptor neuropilin-1 (NRP-1) coincides with expression of Brachyury and VEGFR-2 and identifies endothelial precursors in murine and human embryonic stem cells before CD31 or CD34 expression. Three Key Variables Involved in Feeder Preparation for the Maintenance of Human Embryonic Stem Cells Three variables have been evaluated with respect to feeder preparation and MMC involvement, including mEF exposure to MMC, density of feeder cells, and different wash steps during the preparation of feeder cells. Relative Developmental Toxicity of Glycol Ether Alkoxy Acid Metabolites in the Embryonic Stem Cell Test as Compared to the in Vivo Potency of Their Parent Compounds The aim of the present study was to evaluate the relative sensitivity of the embryonic stem cell test for a selected series of homologous compounds and to compare the data to the relative developmental toxicity of the compounds in vivo. Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and Quantitative Comparison of the Membrane Proteomes of Self-renewing and Differentiating Human Embryonic Stem Cells This study describes complete SILAC labeling of hESCs with fully preserved pluripotency, self-renewal capabilities, and overall proteome status that was quantitatively analyzed to a depth of 1556 proteins and 527 phosphorylation events. Multiplexed Staining of Live Human Embryonic Stem Cells for Flow Cytometric Analysis of Pluripotency Markers To circumvent sample variability the researchers have developed a reproducible, quick and cost effective method of staining 12 populations of hESC grown under different conditions by labeling each with a unique optical signature. INDUSTRY PerkinElmer and Accelrys Announce Software Collaboration to Enable New Single Cell Imaging and Analysis Techniques PerkinElmer, Inc announced a cellular imaging and analysis software relationship with Accelrys, Inc. Pfizer Licenses University of Wisconsin Stem Cells Pharmaceutical giant Pfizer Inc. has agreed to license human embryonic stem cell patents from the University of Wisconsin-Madison for the development of new drug therapies. CIRM Doles Out $67M in Early Translational Grants The California Institute for Regenerative Medicine has chalked up a plan to fund 15 grants with $67.7 million that are all focused on moving basic research toward patients. 2 Columbus Companies Up For High-tech Cash Ohio companies working on fuel cells, stem cells, medical device technology and in the pharmacology sector have been targeted to receive approximately $39 million from a state research and development program. Invitrogen Develops New Technology to Promote Safer Stem Cell Therapies Invitrogen, a division of Life Technologies recently announced a new technology to enable the development of safer stem cell therapies. POLICY Obama Cools the Stem Cell Debate While juggling a collapsing economy and major initiatives during his first months in office, President Obama tackled - and cooled - the contentious issue of embryonic stem cell research. Republican Senator Pushes Biotech Funding A Senate Republican who could prove a swing vote in the U.S. healthcare debate said recently he wanted a new agency to help struggling biotech companies as part of a future healthcare system. California's Stem Cell Scientists Fear Federal Red Tape California researchers are worried that the expected limits could still cause them aggravation if they don't jibe with standards set out by their own funding body, the California Institute of Regenerative Medicine. Translational Stem Cell Research Programme - Response Mode Funding Funding for translational stem cell research is available through a new funding stream led by the MRC as part of the MRC/NIHR single health research strategy. South Korea Lifts Ban on Stem Cell Research South Korea on Wednesday conditionally lifted a ban on stem cell research using human eggs, three years after outlawing the practice because a scientist was found to have faked his work.  Learn more about Embryonic Stem Cell News:  Archives  |  Events   |  Subscribe   |  Contact Us This email was sent by: Connexon Creative 400-570 W. 7th Avenue Vancouver, British Columbia V5Z 1B3 Canada