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TOP STORIES

Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins
This study reports the generation of stable iPSCs from human fibroblasts by directly delivering four reprogramming proteins (Oct4, Sox2, Klf4, and c-Myc) fused with a cell-penetrating peptide (CPP).

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SCIENCE

Healing With Light? Optical Technology Controls Living Cells
A new optical technology that lines up living cells and controls their movements has opened the door to better artificial tissues and wounds that heal faster with less scarring.

Engineered Circuits Can Count Cellular Events
MIT and Boston University engineers have designed cells that can count and "remember" cellular events, using simple circuits in which a series of genes are activated in a specific order.

Combined Stem Cell-gene Therapy Approach Cures Human Genetic Disease in Vitro
A study led by researchers at the Salk Institute for Biological Studies, has catapulted the field of regenerative medicine significantly forward, proving in principle that a human genetic disease can be cured using a combination of gene therapy and induced pluripotent stem cell technology.

Chinese Researchers Find Way to Make Pig Stem Cells
Researchers have found a way to transform ordinary cells from pigs into powerful stem cells in a move that may have implications for human health.

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ABSTRACTS

Generation of Induced Pluripotent Stem Cells from Human Blood
This paper describe the derivation of induced pluripotent stem cells from CD34+ mobilized human peripheral blood cells using retroviral transduction of OCT4/SOX2/KLF4/MYC. (Blood)

A Common Bipotent Progenitor Generates the Erythroid and Megakaryocyte Lineages in Embryonic Stem Cell-derived Primitive Hematopoiesis
Using hematopoietic differentiation of human embryonic stem cells on the OP9 cell line, the researchers identified a primitive MEP in a subset of cells co-expressing glycophorin A and CD41 from day 9 to day 12 of co-culturing. (Blood)

Emerging Potential of Transposons for Gene Therapy and Generation of Induced Pluripotent Stem Cells
The use of non-viral gene delivery approaches in conjunction with the latest generation transposon technology based on Sleeping Beauty or piggyBac transposons may potentially overcome stable gene transfer problems. (Blood)

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INDUSTRY

Commercial Partnership with STEMCELL Technologies Inc
ENKAM Pharmaceuticals A/S is pleased to announce that it has signed a licensing and development agreement with STEMCELL Technologies Inc, which is a leader in specialty cell culture media, cell separation products and ancillary reagents for life science research.

Cellular Dynamics Licenses Key Patent Portfolio Surrounding Cardiovascular Progenitor Cells
Further broadening its leading IP position, Cellular Dynamics International recently announced that it has exclusively licensed a key patent portfolio for the differentiation of stem cells into human cardiovascular progenitor cells.

£4m Grant for Stem Cell Research
A £4 million British Government grant has been awarded to scientists conducting research into stem cell treatments for broken bones.



POLICY

Maryland Stem Cell Research Commission Public Meeting Notice

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