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TOP STORIES

Stem Cell Surprise for Tissue Regeneration
Scientists have overturned previous research that the genes that make muscle stem cells in the embryo are surprisingly not needed in adult muscle stem cells to regenerate muscles after injury.

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SCIENCE

VIDEO: An introduction to a new and innovative way of making uniform, size-controlled embryoid bodies.

Possible Cure Found for Crohn's Disease
Initial findings from the world's first controlled trial of the procedure have raised hopes that it could banish the disease's symptoms for many years in up to half of the patients who undergo it.

Xie Lab Uncovers Molecular Machinery Related to Stem Cell Fate
The Stowers Institute's Xie Lab has revealed how the BAM protein affects germline stem cell differentiation and how it is involved in regulating the quality of stem cells through intercellular competition.

Like Burrs on Your Clothes, Virus-size Capsules Stick to Cells to Target Drug Delivery
It is now possible to engineer tiny containers the size of a virus to deliver drugs and other materials with almost 100 percent efficiency to targeted cells in the bloodstream.

Stem Cells Created From Pigs' Connective Tissue Cells
Scientists at the University of Missouri have developed the ability to take regular cells from a pig's connective tissues, known as fibroblasts, and transform them into stem cells, eliminating several potential side effects.

Dutch Researchers Find First Evidence that Female Human Embryos Adjust the Balance of X
Dutch researchers have found the first evidence that a process of inactivating the X chromosome during embryo development and implantation does in fact take place in human female embryos prior to implantation in the womb.

The University of Pittsburgh Cancer Institute Joins ExCell Research Study Using Stem Cells for Leukemia and Lymphoma Patients
The phase III study is assessing the safety and efficacy of StemEx(R), an investigational product derived from stem cells, as an alternative treatment to bone marrow transplants for hematological malignancies, including leukemia and lymphoma.

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ABSTRACTS

Functional Pre- mRNA trans-Splicing of Coactivator CoAA and Corepressor RBM4 during Stem/Progenitor Cell Differentiation
During stem/progenitor cell neural differentiation, the researchers found that the switched alternative splicing and trans-splicing between CoAA and RBM4 transcripts result in lineage-specific expression of wild type CoAA, RBM4, and their variants. (Journal of Biological Chemistry)

Derivation of Functional Mature Neutrophils from Human Embryonic Stem Cells
The researchers in this study have developed a method to induce hESCs to differentiate into mature neutrophils. (Blood)

Immortalized Human Skin Fibroblast Feeder Cells Support Growth and Maintenance of Both Human Embryonic and Induced Pluripotent Stem Cells
This study established a conditionally immortalized human foreskin fibroblast line that secreted basic fibroblast growth factor. (Human Reproduction)

Birth of Parthenote Mice Directly from Parthenogenetic Embryonic Stem Cells
This study found that derivation of parthenogenetic embryonic stem cells are more efficient than of fESC, in association with reduced MAPK signaling in parthenogenetic embryos and their ICM outgrowth. (Stem Cells)

Establishment of a Cell Line Derived from Mouse Fetal Liver that Have the Character to Promote the Hepatic Maturation of Mouse Embryonic Stem Cells by Co-culture Method
The present study established a murine fetal liver stromal cell line that induced hepatic maturation in mouse embryonic stem cells and hepatic progenitor cells. (Tissue Engineering Part A)

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INDUSTRY

Connexon Creative Launches Cord Blood News
Cord Blood News is a weekly e-newsletter that keeps members of the cord blood community informed by providing the latest news from all areas of the field, including its science, research, policy, and business.

GE Healthcare and Geron Announce Exclusive Global Agreement to Commercialize Stem Cell Drug Discovery Technologies
GE Healthcare and Geron Corporation recently announced that they have entered into a global exclusive license and alliance agreement to develop and commercialize cellular assay products derived from human embryonic stem cells for use in drug discovery, development and toxicity screening.

Ohio's Third Frontier Commission Awards $5 Million to Stem Cell Research
Ohio's Third Frontier Commission has awarded $5 million to a stem cell research center run by Case Western Reserve University, University Hospitals and Athersys.

StemCells, Inc. to be Added to Russell 3000 Index
StemCells, Inc. announced recently its expected addition to the Russell 3000(R) Index on June 26, 2009, when Russell Investments reconstitutes its comprehensive set of U.S. and global equity indexes.

Pluristem Therapeutics Was Awarded a $1.9 Million Grant From the Office of the Chief Scientist in the Israeli Government
Pluristem Therapeutics Inc. announced recently that the company was awarded a $1.9 million government grant from the Office of the Chief Scientist at the Ministry of Industry, Trade and Labor of Israel.



POLICY

Senator Cardin Pledges to Fight for Biotech Funding
Some local life sciences players urged congressional leaders to significantly hike the amount of federal funding for small business research grants in testimony for a Senate committee hearing on whether the stimulus bill missed the boat with smaller biotechs.

State Panel Critical of California Stem Cell Institute
After an eight-month study, California's Little Hoover Commission yesterday released a 70-page report that said the stem cell institute's structure "is not adequate to protect taxpayers' interests or serve its own ambitious goals."

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