CURRENT PUBLICATIONS

Allogeneic Mesenchymal Stem Cells Restore Cardiac Function in Chronic Ischemic Cardiomyopathy via Trilineage Differentiating Capacity
Findings demonstrate long-term MSC survival, engraftment, and trilineage differentiation following transplantation into chronically scarred myocardium. [PNAS]

Fully Functional Bioengineered Tooth Replacement as an Organ Replacement Therapy
Scientist report a successful fully functioning tooth replacement in an adult mouse achieved through the transplantation of bioengineered tooth germ into the alveolar bone in the lost tooth region. [PNAS]

In vivo Myocardial Distribution of Multipotent Progenitor Cells Following Intracoronary Delivery in a Swine Model of Myocardial Infarction
Using an anterior myocardial infarction swine model, near-infrared fluorescence was used for in vivo tracking of labeled mesenchymal stromal cells, bone marrow mononuclear and peripheral blood mononuclear cells early after intracoronary injection. [European Heart Journal]

Adipose Tissue Mesenchymal Stem Cell Expansion in Animal Serum-Free Medium Supplemented with Autologous Human Platelet Lysate
Platelets provided by a single donor are sufficient to obtain platelet lysate (PL) for human adipose mesenchymal stem cell (hASC) propagation for clinical-scale applications mitigating the potential untoward side effects associated with the use of animal-derived reagents. [Transfusion]

Regenerative Effects of Transplanted Mesenchymal Stem Cells in Fracture Healing
In this study, using a stabilized tibia fracture mouse model, scientists determined the dynamic migration of transplanted MSC to the fracture site, their contributions to the repair process initiation, and their role in modulating the injury-related inflammatory responses. [Stem Cells]

Generation of Pancreatic Hormone-Expressing Islet-Like Cell Aggregates from Murine Adipose Tissue-Derived Stem Cells
Data presented here demonstrate the feasibility of using ASCs as a source of autologous stem cells to differentiate into the pancreatic lineage. [Stem Cells]

Efficient Adipocyte and Osteoblast Differentiation from Mouse Induced Pluripotent Stem Cells by Adenoviral Transduction
Results suggest that Ad vector-mediated transient transduction is sufficient to increase cellular differentiation and that our transduction methods would be useful for therapeutic applications based on iPS cells. [Stem Cells]

Therapeutic Benefit of Human Umbilical Cord Derived Mesenchymal Stromal Cells in Intracerebral Hemorrhage Rat: Implications of Anti-inflammation and Angiogenesis
Intracerebral administration of UC-MSC could accelerate neurological function recovery of ICH rat, the underlying mechanism may ascribe to their ability to inhibit inflammation and promote angiogenesis. [Cell Physiol Biochem]

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