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Mesenchymal Cell News 1.01, September 8, 2009. Click here if you are unable to see images in this e-mail.
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TOP STORIES

Osiris Therapeutics Announces Preliminary Results for Prochymal Phase III GvHD Trials
Osiris Therapeutics, Inc. today announced preliminary results for two phase III trials evaluating Prochymal for the treatment of acute graft versus host disease (GvHD). [Osiris Therapeutics, Inc., Columbia]

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SCIENCE NEWS

New Stem Cell Treatment 'Being Used by Patients to Avoid Hip Replacements'
British scientists have developed a stem cell technique which is being used by patients to avoid hip replacements, in a major medical breakthrough. [Southampton Hospital, Southampton]

'Liposuction Leftovers' Easily Converted to iPS Cells, Study Shows
Globs of human fat removed during liposuction conceal versatile cells that are more quickly and easily coaxed to become induced pluripotent stem cells than are the skin cells most often used by researchers. [Stanford School of Medicine, Palo Alto]

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CURRENT PUBLICATIONS

Allogeneic Human Mesenchymal Stem Cells for Treatment of E. coli Endotoxin-Induced Acute Lung Injury in the Ex Vivo Perfused Human Lung
Treatment with allogeneic human MSCs or the conditioned medium restores normal fluid balance in an ex vivo perfused human lung injured by E. coli endotoxin. [PNAS]

Encapsulated Human Mesenchymal Stem Cells: a Unique Hypoimmunogenic Platform for Long-term Cellular Therapy
Researchers designed alginate-PLL microcapsules that can encapsulate human mesenchymal stem cells for extended periods, as demonstrated by fluorescence and H3-thymidine assays. [FASEB J]

Autocrine and Paracrine Angiopoietin 1/Tie-2 Signaling Promotes Muscle Satellite Cell Self-Renewal
This paper studied the role of angiopoietin 1 and its receptor Tie-2 in the regulation of myogenic precursor cell fate. [Cell Stem Cell]

Differentiation of Mesenchymal Stromal Cells Derived from Umbilical Cord Wharton's Jelly into Hepatocyte-Like Cells
Umbilical Cord MSC can differentiate into functional hepatocyte-like cells following the induction of hepatotic growth factor (HGF) and fibroblast growth factor-4 (FGF-4). UC MSC can serve as a favorable cell source for tissue engineering in the treatment of liver disease. [Cytotherapy]

Differential Effects of X-Rays and High-Energy 56Fe Ions on Human Mesenchymal Stem Cells
This study was designed to compare the biological effects of X-rays and of high-linear energy transfer 56Fe ions on human mesenchymal stem cells. [Int J Radiat Oncol Biol Phys] 

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INDUSTRY NEWS

STEMCELL Technologies Inc. to Host Stem Cell Training Courses
STEMCELL's fall training program includes includes 2-day courses on mesenchymal stem cell biology, mammary stem cell biology, neural stem cell biology, hematopoietic stem cell biology, and human embryonic and induced pluripotent stem cell biology.

geneX® Used in Pioneering Stem Cell Research
Professor James B. Richardson of the Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, UK has been carrying out pioneering work combining geneX with selected and culture expanded Mesenchymal stem cells to treat fracture non-unions.

US Patent and Trademark Office Publishes Stemedica's Patent Application for the Treatment of Diabetic Retinopathy.
Stemedica's invention relates to the use of multiple stem cells and a transplantation methodology in the treatment of Diabetic Retinopathy. Patients received neural progenitor cells by retrobulbar injection and mesenchymal stem cells administered intravenously.

BloodStor(TM) Stem Cell Biopreservation Media Platform Launched by BioLife Solutions
BioLife Solutions Inc. today announced the launch of its BloodStor biopreservation media product platform. The product family includes BloodStor™ 55-5 for cryopreservation of umbilical cord blood stem cells, as well as other variants for peripheral blood derived stem cells.


POLICY NEWS

Safety Call Over Stem Cell Trips
A clampdown on unproven and potentially unsafe stem cell research is being called for by an expert group.

Maryland Stem Cell Research Commission Public Meeting Notice

FOOD AND DRUG ADMINISTRATION (United States)

FDA Study Indicates Most Industry Postmarketing Studies Meet Timelines
Makers of approved drugs and biologics generally are meeting their regulatory obligations and complete their postmarketing studies in a timely manner, according to a recent study.

NATIONAL INSTITUTES OF HEALTH (United States)

Clarification of NOT-OD-08-014 Regarding Obtaining Assistance from NIH for Registration and Reporting of Results in ClinicalTrials.gov (NOT-OD-09-147)

Enhancing Peer Review: The NIMH Announces Consolidation of Review Criteria for NIMH Career Opportunities in Research (COR) Honors Undergraduate Research Training Grant (T34) Submitted for FY 2010 Funding (NOT-MH-09-018)



EVENTS

XXXVI Annual meeting European Society for Artificial Organs 2009
September 2-5, 2009, Compiègne, France

International Society for Hematology and Stem Cells 38th Annual Scientific Meeting
September 9-12, 2009, Athens, Greece

2009 Stem Cells Europe/ World Biobanking Summit
September 23-25, 2009, Edinburgh, United Kingdom

World Stem Cell Summit 2009
September 23-25, 2009, Baltimore, MD, United States

Mesenchymal Stem Cell Conference 2009
November 12-14, 2009, Austin, TX, United States

Molecular Tri Conference & The Stem Cell Meeting
February 2-5, 2010, San Francisco, CA, United States

Blood and Marrow Transplantation
February 24-28, 2010, Orlando, FL, United States

World Congress Regenerative Medicine
March 12-14, 2010, Bangkok, Thailand

The European Group for Blood & Marrow Transplantation Annual Meeting
March 21-24, 2010, Vienna, Austria

9th Transgenic Technology Meeting
March 22-24, 2010, Berlin, Germany

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