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CURRENT PUBLICATIONS

Endovenous Administration of Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells Prevents Renal Failure in Diabetic Mice
Preclinical results support MSC administration as a cell therapy strategy to prevent chronic renal diseases secondary to diabetes. [Biol Blood Marrow Transplant]

Encapsulated Human Mesenchymal Stem Cells: A Unique Hypoimmunogenic Platform for Long-Term Cellular Therapy
In vitro and in vivo immunogenicity studies revealed that encapsulated hMSCs were significantly hypoimmunogenic, leading to a 3-fold decrease in cytokine expression compared to entrapped cell lines. [FASEB J]

Bi-Directional Activation Between Mesenchymal Stem Cells and CLL B-cells: Implication for CLL Disease Progression
In MSC, rapid ERK and AKT phosphorylation were detected when chronic lymphocytic leukaemia B-cells and MSC were separated by transwell; indicating that activation of MSC was mediated by soluble factors. [Br J Haematol]

Mesenchymal Stem Cells Produce Wnt Isoforms and TGFBeta1 that Mediate Proliferation and Pro-Collagen Expression by Lung Fibroblasts
Data demonstrate that MSC from mice and humans produce Wnt proteins and TGFBeta-1 that respectively stimulate LF proliferation and matrix production, two hallmarks of fibroproliferative lung disease. [Am J Physiol Lung Cell Mol Physiol]

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