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SCIENCE NEWS
Complimentary Webinar: Defined, Serum-Free Culture of MSCs using MesenCult®-ACF Medium
Researchers at Hohenstein Successfully Colonise a Textile Implant with Human Stem Cells Researchers have developed a method to embed multipotent mesenchymal stem cells onto the surface fibers of common surgical fabric implants. [Hohenstein Institute, Stuttgart]
Rare Genetic Disease Successfully Reversed Using Stem Cell Transplantation In research that holds out hope for one day developing a potential therapy to treat the fatal disorder cystinosis, the study shows that the genetic defect in mice can be corrected with stem cell transplantation. [Scripps Research Institute, La Jolla]
Enrolment Complete for Second Group of Heart Failure Patients Treated with "Off-The-Shelf" Adult Stem Cells Mesoblast Limited, today announced successful completion of enrolment of the second group of 20 patients randomised to receive an increased dose of Revascor™, the proprietary allogeneic, or "off-the-shelf", universal adult stem cell product for congestive heart failure. [Mesoblast Ltd., Melbourne]
Bioheart Inc. Announces Positive Results in the MARVEL Phase II/III Clinical Trial Bioheart, Inc. recently presented positive efficacy data from part 1 of its Phase II/III clinical trial involving the injection of adult muscle stem cell therapy into patients' damaged heart muscle. [Bioheart Inc., Sunrise]

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CURRENT PUBLICATIONS
Hepatocyte Growth Factor or Vascular Endothelial Growth Factor Gene Transfer Maximizes Mesenchymal Stem Cell-Based Myocardial Salvage After Acute Myocardial Infarction
Hepatocyte growth factor (HGF) and VEGF are cardioprotective by increasing the tolerance of cardiomyocytes to ischemia, reducing cardiomyocyte apoptosis and increasing prosurvival Akt activation, and MSC-HGF and MSC-VEGF are a valuable source for increased cytokine production and maximize the beneficial effect of MSC-based repair strategies. [Circulation]
Mesenchymal Cell Transplantation and Myocardial Remodeling After Myocardial Infarction This paper attempted to determine whether and to what degree left ventricular remodeling may be affected by mesenchymal precursor cells injection post-myocardial infarction, and whether these effects are concentration-dependent. [Circulation]
Successful Treatment of the Murine Model of Cystinosis Using Bone Marrow Cell Transplantation Using the murine model for cystinosis, Ctns-/- mice, researchers performed syngeneic bone marrow cell, hematopoietic stem cell, and mesenchymal stem cell transplantation. [Blood]
Comparison of ex Vivo Expansion Culture Conditions of Mesenchymal Stem Cells for Human Cell Therapy The aim of this study is to compare the culture of bone marrow-derived MSCs in the presence of different serum supplements to determine the effect on cell growth, differentiation potential, and immunologic function. [Transfusion]
Therapeutic Benefit of Human Umbilical Cord Derived Mesenchymal Stromal Cells in Intracerebral Hemorrhage Rat: Implications of Anti-inflammation and Angiogenesis Intracerebral administration of UC-MSC could accelerate neurological function recovery of ICH rat, the underlying mechanism may ascribe to their ability to inhibit inflammation and promote angiogenesis.
[Cell Physiol Biochem]
Spontaneous Differentiation of Murine Bone Marrow-Derived Mesenchymal Stem Cells into Adipocytes without Malignant Transformation after Long-Term Culture
Murine bone marrow-derived Mesenchymal Stem Cells (bMSCs) can be propagated in vitro for up to 50 passages with no malignant transformation sign under suitable conditions, but how to sustain their pluripotent potential requires further investigation. [Cell Physiol Biochem]
Cotransplantation with Mesenchymal Stromal Cells Improves Engraftment of Hematopoietic Stem Cells After Autologous Intra-bone marrow Transplantation in Nonhuman Primates Here, using nonhuman primates, the researchers investigated the effects of cotransplantation with mesenchymal stromal cells on the engraftment of hematopoietic stem cells after autologous intra-bone marrow transplantation.
[Exp Hematol]

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EVENTS
Mesenchymal Stem Cell Conference 2009 November 12-14, 2009, Austin, TX, United States
Molecular Tri Conference & The Stem Cell Meeting February 2-5, 2010, San Francisco, CA, United States
Blood and Marrow Transplantation February 24-28, 2010, Orlando, FL, United States
World Congress Regenerative Medicine March 12-14, 2010, Bangkok, Thailand
The European Group for Blood & Marrow Transplantation Annual Meeting March 21-24, 2010, Vienna, Austria
9th Transgenic Technology Meeting
March 22-24, 2010, Berlin, Germany
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