TOP STORIES

Prospective Identification, Isolation, and Systemic Transplantation of Multipotent Mesenchymal Stem Cells in Murine Bone Marrow
In this study, the researchers used phenotypic, morphological, and functional criteria to identify and prospectively isolate a subset of MSCs (PDGFR{alpha}+Sca-1+CD45-TER119-) from adult mouse bone marrow. [JEM]

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SCIENCE NEWS

Reprogramming a Patient's Eye Cells May Herald New Treatments Against Degenerative Disease
The research is the first proof in principle that somatic, or body cells, can be reprogrammed into induced pluripotent stem cells simply through the influence of the microenvironment in which the sampled cells are cultured. [University of Nebraska Medical Center, Omaha]

"Scaffold" Developed to Regenerate Lost or Damaged Bones and Tissues
Scientists have developed a new biologically active "scaffold" made from soluble fibers, which may help humans replace lost or missing bone. [Tel Aviv University, Tel Aviv]

Growing Cartilage from Stem Cells
Using adult stem cells from bone marrow and skin as well as human embryonic stem cells, researchers have grown cartilage tissue in the lab. [University of California - Davis, Davis]

Scientists Identify Specific Markers that Trigger Aggressiveness of Liver Cancer
Researchers investigated the molecular mechanisms of hepatocellular carcinoma and are the first to provide a comprehensive profile of multiple Epithelial-Mesenchymal Transition markers. [Taipei Veterans General Hospital, Taipei]

CURRENT PUBLICATIONS

Priming Integrin {alpha}5 Promotes Human Mesenchymal Stromal Cell Osteoblast Differentiation and Osteogenesis
Using transcriptome analysis, the researchers found that integrin {alpha}5 (ITGA5) expression is up-regulated during dexamethasone-induced osteoblast differentiation of human mesenchymal stromal cells. [PNAS]

Unique Biomechanical Interactions Between Myeloma Cells and Bone Marrow Stroma Cells
The researchers observed that bone-marrow-stromal-cells from myeloma patients were significantly stiffer than control BMSCs using a cytocompression device. [Prog Biophys Mol Biol]

Heparinized Micropatterned Surfaces for the Spatial Control of Human Mesenchymal Stem Cells
In this study, a heparinized micropattern surface was prepared for the spatial control of human mesenchymal stem cells that can differentiate into the desired tissues. [J Bioact Compat Polym]

Isolation and Characterization of Murine Multipotent Lung Stem Cells
The isolation and characterization of resident progenitor/stem cells from adult mouse lung showed differentiation into endothelial and lung epithelial cells and some mesenchymal but no neural differentiation ability. [Stem Cells Dev]

Myogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells on a 3D Nano Fibrous Scaffold for Bladder Tissue Engineering
This group investigated the effects of soluble growth factors, bladder extracellular matrix, and 3D dynamic culture on cell proliferation and differentiation of human bone marrow mesenchymal stem cells into smooth muscle cells. [Biomaterials]

Thermosensitive Injectable Hyaluronic Acid Hydrogel for Adipose Tissue Engineering
This newly described thermoresponsive AHA-g-PNIPAAm copolymer demonstrated attractive properties to serve as cell or pharmaceutical delivery vehicles for a variety of tissue engineering applications. [Biomaterials]

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INDUSTRY NEWS

Gamida Cell and Cellerix Partner on Feasibility Study
Gamida Cell Ltd. and Cellerix, S.A. announced recently that the companies are collaborating on a feasibility study to evaluate the added value of combining the proprietary technologies of each.

Faust says Harvard Assessing Options on Science Complex
Harvard President Drew Faust said that the university is in the midst of re-assessing options for its long-planned expansion into Allston, including the possibility of "re-imagining" its $1 billion science complex.

Shorenstein, SKS Near $1B Project
Shorenstein Properties and SKS Investments have a preliminary agreement with the city of South San Francisco to build 2.3 million square feet of waterfront biotech research and development space at Oyster Point.

POLICY NEWS

California and China Agree to Collaborate on Stem Cells
The California Institute for Regenerative Medicine and the Chinese Ministry of Science and Technology have agreed to collaborate on stem cell research.

South Korea Clone Scientist Convicted
A South Korean court has convicted the disgraced cloning scientist Hwang Woo-suk of fraud over his stem-cell research.

Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P) List of Registered Establishments

EVENTS

Mesenchymal Stem Cell Conference 2009
November 12-14, 2009
Austin, United States

Association for Molecular Pathology 15th Annual Meeting
November 19-22, 2009
Kissimmee, United States

3rd Congress on Non-Hematopoietic Stem Cells
November 20-21, 2009
Tubingen, Germany

Stem Cells World Congress
January 19-20, 2010
San Francisco, United States

Molecular Tri Conference & The Stem Cell Meeting
February 3-5, 2010
San Francisco, United States

2010 Bone Marrow Transplant Tandem Meetings
February 24-28, 2010
Orlando, United States

World Congress Regenerative Medicine
March 12-14, 2010
Bangkok, Thailand

The European Group for Blood & Marrow Transplantation Annual Meeting
March 21-24, 2010
Vienna, Austria

9th Transgenic Technology Meeting
March 22-24, 2010
Berlin, Germany

American Society of Clinical Oncology Annual Meeting
June 4-8, 2010
Chicago, United States

16th Annual ISCT meeting
May 23-26, 2010
Philadelphia, United States

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