TOP STORIES

Successful Bone Marrow Regeneration in Cancer Patients Using Cord Blood Expanded by Proprietary Stem Cells
Mesoblast Limited recently announced that the proprietary mesenchymal precursor cells expanded hematopoietic stem cells in umbilical cord blood by approximately 40-fold. [Mesoblast Limited, Melbourne]

SPECIAL FEATURES

Video: Learn How to Obtain More MSCs in Fewer Passages with MesenCult®-ACF than with Serum-based Medium

SCIENCE NEWS

CURRENT PUBLICATIONS

Combining Neuropeptide Y and Mesenchymal Stem Cells Reverses Remodeling After Myocardial Infarction
This paper describes Neuropeptide Y's induced differentiation of bone marrow derived-mesenchymal stem cells into cardiomyocytes following transplantation into infarcted myocardium. [Am J Physiol Heart Circ Physiol]

Mesenchymal Stem Cells Respond to TNF But Do Not Produce TNF
Here, the researchers elaborate on a previous study by demonstrating that although unrestricted somatic stem cells do not produce Toll-like receptors, they are susceptible to TNF stimulation, resulting in NF-{kappa}B translocation and cytokine production. [J Leukoc Biol]

Bi-directional Activation Between Mesenchymal Stem Cells and CLL B-cells: Implication for CLL Disease Progression
This study tested the hypothesis that contact between chronic lymphocytic leukemia B-cells and marrow stromal cells impact both cell types. [Br J Haematol]

Autologous Bone Marrow-derived Cells for Healing Excisional Dermal Wounds of Rabbits
The wound-healing potential of autologous bone marrow-derived nucleated cells was evaluated in full-thickness skin wounds in the thoracolumbar region of 20 clinically healthy rabbits. [Vet Rec]

Bone Marrow Mesenchymal Stem Cells from Leukemia Patients Inhibit Growth and Apoptosis in Serum-deprived K562 Cells
The regulation of growth and apoptosis in K562 cells by human bone marrow mesenchymal stem cells from leukemia patients was investigated. [J Exp Clin Cancer Res]

Injectable Biodegradable Hydrogels with Tunable Mechanical Properties for the Stimulation of Neurogenesis Differentiation of HumMn mesenchymal Stem Cells in 3D Culture
This study reports an injectable hydrogel scaffold system with tunable stiffness for controlling the proliferation rate and differentiation of human mesenchymal stem cells in a three-dimensional context in normal growth media. [Biomaterials]

Galectin-1 and Semaphorin-3A are Two Soluble Factors Conferring T Cell Immunosuppression to Bone Marrow Mesenchymal Stem Cell
In this study, the researchers show that both Galectin-1 and Semaphorin-3A (Sema-3A), two soluble factors capable to inhibit T cell proliferation through neuropilin-1 (NP-1) binding, are highly expressed by MSCs and may account for their known suppressive activities. [Stem Cells Dev]

INDUSTRY NEWS

Gladstone and Stanford in Collaboration to Develop Induced Pluripotent Stem Cells for Cardiac Therapies
Scientists at the Gladstone Institute of Cardiovascular Disease and Stanford University School of Medicine will collaborate in a new consortium funded by the National Heart, Lung and Blood Institute to develop stem cell and regenerative medicine therapies.

Stem Cell Therapy International, Inc. and Histostem Korea Announce $5 Million Financing Commitment
Stem Cell Therapy International Inc. and its soon to be subsidiary, Histostem Ltd. of South Korea, announced that they have entered into a definitive agreement for up to a $5 million investment commitment with Socius Life Science Capital Group, LLC.

To Heal Diabetic Foot Ulcers, A New Drug Harnesses Stem Cells Inside Us All
Diabetic foot ulcers are the primary cause of hospital admissions for diabetics, but now science has found a way of mobilizing stem cells within the body to treat this health issue.

POLICY NEWS

Stem Cell Research Bringing Jobs and Innovation to Ontario, Canada
Ontario, Canada is supporting a world-class stem cell research project to help revolutionize treatments for major health conditions like cancer, heart disease and traumatic injuries, and create high-value jobs in Toronto.

Bill Could Strictly Regulate Stem Cell Research
Michigan State University researchers are concerned regulations on embryonic stem cell research proposed in a Michigan Senate Committee would interfere with their progress.

EVENTS

Mesenchymal Stem Cell Conference 2009
November 12-14, 2009
Austin, United States

3rd Congress on Non-Hematopoietic Stem Cells
November 20-21, 2009
Tubingen, Germany

Stem Cells World Congress
January 19-20, 2010
San Francisco, United States

Molecular Tri Conference & The Stem Cell Meeting
February 3-5, 2010
San Francisco, United States

2010 Bone Marrow Transplant Tandem Meetings
February 24-28, 2010
Orlando, United States

World Congress Regenerative Medicine
March 12-14, 2010
Bangkok, Thailand

The European Group for Blood & Marrow Transplantation Annual Meeting
March 21-24, 2010
Vienna, Austria

9th Transgenic Technology Meeting
March 22-24, 2010
Berlin, Germany

American Society of Clinical Oncology Annual Meeting
June 4-8, 2010
Chicago, United States

16th Annual ISCT meeting
May 23-26, 2010
Philadelphia, United States

JOB OPPORTUNITIES

Manager, Market Segment Regenerative Medicine (Sigma-Aldrich Corporation)

Technical Specialist (AABB)

R&D Scientist (STEMCELL Technologies)

Technical Support Representative - France (STEMCELL Technologies)

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