|
|
 |
|
|
TOP STORY
Synovial Sarcoma is a Stem Cell Malignancy
Collectively, these data suggest that a human multipotent mesenchymal stem cell can serve as a cell of origin for synovial sarcoma (SS) and SS is a stem cell malignancy resulting from dysregulation of self-renewal and differentiation capacities driven by SS18-SSX fusion protein. [Stem Cells]
|
|
CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal)
DNAJB6 Induces Degradation of Beta-Catenin and Causes Partial Reversal of Mesenchymal Phenotype
Researchers revealed that MRJ(L) expression causes changes in cell morphology concomitant with down-regulation of several mesenchymal markers viz. Vimentin, N-cadherin, Twist, Slug and up-regulation of epithelial marker, Keratin 18. [J Biol Chem]
Polyampholytes as Cryoprotective Agents for Mammalian Cell Cryopreservation
The results indicate that these polymeric extracellular cryoprotective agents (CPAs) may replace current CPAs and the high viability after thawing and non-necessity of serum ensure that these CPAs may be used in various preservation fields. [Cell Transplant]
Non-Senescent Hsp27-Upregulated MSCs Implantation Promote Neuroplasticity in Stroke Model
In this study, researchers demonstrated that implantation of human umbilical cord mesenchymal stem cells cultured in human umbilical cord serum significantly enhanced neuroplasticity and angiogenesis in stroke and ischemic limb models. [Cell Transplant]
Loss of Stromal Caveolin-1 Leads to Oxidative Stress, Mimics Hypoxia and Drives Inflammation in the Tumor Microenvironment, Conferring the "Reverse Warburg Effect": A Transcriptional Informatics Analysis with Validation
Using an unbiased informatics analysis of the transcriptional profile of Cav-1 (-/-) deficient mesenchymal stromal cells, researchers have now identified many of the major signaling pathways that are activated by a loss of Cav-1, under conditions of metabolic restriction (with low glucose media). [Cell Cycle]
In Vitro Screening System for Hepatotoxicity: Comparison of Bone Marrow-Derived Mesenchymal Stem Cells and Placenta-Derived Stem Cells
Placenta-derived stem cells (PDSCs) have been spotlighted as a new cell source in stem cell research recently because they are characterised by their capacity to differentiate into multiple lineages. However, the use of PDSCs as an in vitro screening model for potential drug candidates has not yet been studied. [J Cell Biochem]
Promotion of Human Adipose-Derived Stem Cell Proliferation Mediated by Exogenous Nucleosides
The results support the importance of the nucleoside supplementation of media to improve conditions for the expansion and maintenance of human adipose-derived stem cells in culture. [Cell Biol Int]
Mesenchymal Stromal Cells for Steroid-Refractory Acute Graft-Versus-Host Disease: A Report of Two Cases
Here researchers have reported two cases of the patients with acute steroid-refractory graft-versus-host disease who underwent allogeneic hematopoietic stem cell transplantation. [Int J Hematol]
|
|
POLICY NEWS
STAR METRICS: New Way to Measure the Impact of Federally Funded Research
A new initiative--Science and Technology for America's Reinvestment: Measuring the Effect of Research on Innovation, Competitiveness and Science, or STAR METRICS--promises to monitor the impact of federal science investments on employment, knowledge generation, and health outcomes. [National Institutes of Health, United States]
Administrative Supplements to Increase Public Awareness of Pediatric Cancers and Available Treatments and Research (NOT-CA-10-026) [National Institutes of Health, United States]
Heart Failure Clinical Research Network Regional Clinical Centers (U10) (RFA-HL-12-001) [National Institutes of Health, United States]
FDA Announces Collaboration with Drugs.com
The U.S. Food and Drug Administration announced that it will collaborate with the website Drugs.com to expand access to the FDA's consumer health information. [Food and Drug Administration, United States]
2010 Biological License Application Approvals [Food and Drug Administration, United States]
2010 Biological Device Application Approvals [Food and Drug Administration, United States]
Emerging Infectious Diseases: Evaluation to Implementation for Transfusion and Transplantation Safety Public Workshop (Update) [Food and Drug Administration, United States]
|
|
EVENTS
Tissue Engineering & Regenerative Medicine International Society (TERMIS) - European Union 2010
June 13-17, 2010
Galway, Ireland
International Society for Stem Cell Research (ISSCR) 8th Annual Meeting
June 16-19, 2010
San Francisco, United States
United Kingdom National Stem Cell Network (UKNSCN) 3rd Annual Scientific Conference
July 12-14, 2010
Nottingham, United Kingdom
Tissue Engineering & Regenerative Medicine International Society (TERMIS) - Asia Pacific 2010
September 15-17, 2010
Sydney, Australia
5th World Congress on Preventative and Regenerative Medicine (WCRM) 2010
October 5-7, 2010
Hannover, Germany
2010 American Society for Matrix Biology (ASMB) Meeting
October 24-27, 2010
Charleston, United States
52nd American Society of Hematology (ASH) Annual Meeting and Exposition
December 4-7, 2010
Orlando, United States
Tissue Engineering & Regenerative Medicine International Society (TERMIS) - North America 2010 Annual Conference
December 5-8, 2010
Orlando, United States
Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.
JOB OPPORTUNITIES
Senior Scientist - Magnetic Cell Separation (STEMCELL Technologies)
Business Development Manager Europe - Cell Therapy Products (Pall Corporation)
Manager/Sr. Manager, Therapeutic Cell Solutions, Process Development (Lonza)
Sr. Product Support and Training Specialist (CardianBCT)
Reach more than 11,000 potential candidates by posting your organization's career opportunities with Mesenchymal Cell News.
Visit here to post your career opportunities.
Have we missed an important article or publication in Mesenchymal Cell News? Click here to submit!
Comments or Suggestions? Email info@connexoncreative.com with your feedback.
|
|
|
|
|
|
|
|
|