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Impaired Brain Plasticity Linked To Angelman Syndrome Learning Deficits
Researchers find that impaired brain plasticity may explain how disruption of a single gene in the brain can cause severe cognitive deficits.



SCIENCE

Medicinal Plant, St John's Wort, May Reduce Neuronal Degeneration Caused By Parkinson's Disease
A research team has carried out a study which suggests that a plant with antidepressant properties has antioxidant active ingredients that could help reduce the neuronal degeneration caused by disease.

Stem Cell Therapeutics Corp. Announces the FDA Has Lifted Its Clinical Hold on the Phase IIb Stroke Trial
Stem Cell Therapeutics Corp. is pleased to announce the U.S. Food and Drug Administration has provided a verbal confirmation to remove its clinical hold placed on NTx(R)-265 on September 18, 2008.

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ABSTRACTS

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Adult Neural Stem/Progenitor Cells Reduce NMDA-induced Excitotoxicity Via the Novel Neuroprotective Peptide Pentinin
This study investigated whether medium conditioned by adult hippocampal stem/progenitor cells altered the extent of excitotoxic cell death in hippocampal slice cultures.

Isolation of Human Multipotent Neural Progenitors from Adult Filum Terminale
The researchers show for the first time that progenitor cells exhibiting the hallmarks of stem cells can be isolated from adult human filum terminale.

Human GPM6A Is Associated With Differentiation and Neuronal Migration of Neurons Derived from Human Embryonic Stem Cells
To investigate the function of GPM6A in neural differentiation, this study generated human ES cell lines with over expressed (B2h-oeM6A) or suppressed (B2h-shM6A) human GPM6A.

In vitro Generation of Murine Myeloid Dendritic Cells from CD34-positive Precursors
Here the researchers demonstrate an isolation procedure of functionally intact myeloid CD11c+ CD11b+ DCs derived from murine CD34-positive precursors.

Alzheimer ß-amyloid Blocks Epileptiform Activity in Hippocampal Neurons
This study tested the effect of Aß1-40 oligomers/aggregates, believed to be involved in Alzheimer's Disease (AD) genesis, on this type of synaptic plasticity.

Characterization of Dendritic Cells and Macrophages Generated by Directed Differentiation from Mouse Induced Pluripotent Stem Cells
The researchers have demonstrated the induction of anti-cancer immunity and prevention of autoimmune disease by in vivo administration of genetically engineered human embryonic-dendritic stem cells.



INDUSTRY

CTR_SS1

Connexon Creative Launches Mammary Cell News
Mammary Cell News is a weekly e-newsletter that keeps members of the mammary cell community informed by providing the latest news from all areas of the field, including its science, research and business.

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STEMSOFT Software Inc. Licenses StemLab Software to Carter BloodCare
STEMSOFT Software Inc, the leading provider software solutions for cell therapy transplant, is pleased to announce the licensing of StemLab, the leading cell therapy and cord blood banking laboratory software, to Carter BloodCare's Stem Cell Transplant Laboratory in Bedford, TX.

ExcellGene and Kuhner Achieved Milestone in Development of Novel 250 Liter Mammalian Cell Culture Bioreactors
As part of a long-term partnership the two companies disclosed recently the successful conclusion of the technically challenging task of growing mammalian cells for the production of recombinant proteins in an orbitally shaken bioreactor.

Advanced Cell Technology Provides Single Blastomere Technology To CHA Bio & Diostech Co., Ltd.
Advanced Cell Technology, Inc. and CHA Bio & Diostech Co., Ltd. announced recently that the parties have entered into a licensing agreement under which Advanced Cell will license its proprietary "single blastomere technology," to CHA Bio for development and commercialization exclusively in Korea.

Maryland Stem Cell Research Commission Announces 59 Projects for Funding
The Maryland Stem Cell Research Commission has completed its evaluation of the 147 applications in response to its three official Requests for Applications.

Lonza Expands Cell Therapy Business with New Facility in Singapore
Lonza Group Ltd is expanding its Cell Therapy business with the construction of a new facility in Singapore.

China to Invest $9.2 Bln in New Technology
China will spend 62.8 billion Yuan ($9.2 billion) this year and the next on new technology as part of its efforts to stimulate economic growth, the State Council said on Wednesday.

University of Haifa Research Team Awarded European Union Research Grant
A research team composed of 14 European groups has been awarded 11.9 million Euros, on behalf of the European Union, to study the role of synaptic proteins in neurological and psychiatric diseases.

Fate Therapeutics Granted Exclusive License for Stem Cell Modulators by Children's Hospital Boston and Massachusetts General Hospital
Fate Therapeutics, Inc. announced recently that it has acquired exclusive intellectual property rights jointly owned by Children's Hospital Boston and Massachusetts General Hospital.

NeoStem Obtains Exclusive License to Innovative Stem Cell Procedure Treating Musculoskeletal Diseases
NeoStem, Inc. announced recently it has signed an exclusive royalty-bearing license agreement for the Asia territory to use an innovative process that rapidly grows a patient's own adult stem cells to treat a variety of musculoskeletal diseases.

Stem Cell Patent Digests
The UKNSCN has embarked upon a pilot project to provide the community with regular digests of both published and granted patents in the stem cell field.

U.S. Patent Office Upholds StemCells' Patents - Company Moves to Resume Patent Infringement Cases Against Neuralstem
StemCells, Inc. announced recently that the U.S. Patent and Trademark Office has upheld the validity of the remaining two neural stem cell patents which were subjected to reexamination proceedings commenced by Neuralstem, Inc.



POLICY

STEMSOFT Software Inc. Releases White Paper on Electronic Records in Cell Therapy - Regulatory and Accreditation Requirements

Bush Bioethics Advisors Take Potshot at Obama Stem Cell Platform
Prestigious Hastings Center bioethics think tank publishes comments by more than half of President Bush's bioethics council.

Obama Talks of Common Ground Amid Notre Dame Protests
Amid protests over his positions on abortion and embryonic stem-cell research, President Obama spoke to graduates at the University of Notre Dame about coming together over disagreements by finding "common ground."

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