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ABSTRACTS
Soluble Oligomers of Amyloid Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake
This study reports that soluble A oligomers from several sources (synthetic, cell culture, human brain extracts) facilitated electrically evoked LTD in the CA1 region. (Neuron)
The Effect of Neurotrophin-3/Chitosan Carriers on the Proliferation and Differentiation of Neural Stem Cells
In this study, the behavior of neural stem cells from the newborn rat spinal cord was compared at neurosphere level after the addition of neurotrophin-3 (NT-3) once or daily, blank chitosan carriers, or NT-3-chitosan carriers respectively. (Biomaterials)
P90 Ribosomal s6 Kinase 2 Negatively Regulates Axon Growth in Motoneurons
The researchers in this study investigated the consequences of Rsk2 deficiency in mouse spinal motoneurons. (Molecular and Cellular Neuroscience)
Endothelial Cells Support Survival, Proliferation and Neuronal Differentiation of Transplanted Adult Ischemia-Induced Neural Stem/Progenitor Cells after Cerebral Infarction
In the present study, the researchers grafted cortex-derived stroke-induced neural stem/progenitor cells, obtained from adult mice, onto post-stroke cortex in the presence or absence of endothelial cells, and compared survival, proliferation and neuronal differentiation of the neural precursors in vivo. (Stem Cells)
Neuroglobin-overexpression Alters Hypoxic Response Gene Expression in Primary Neuron Culture Following Oxygen Glucose Deprivation
In this study the researchers asked how Ngb, a tissue globin specifically expressed in neurons, may help regulate genes responsive to hypoxia. (Neuroscience)
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INDUSTRY
Connexon Creative Launches Cord Blood News
Cord Blood News is a weekly e-newsletter that keeps members of the cord blood community informed by providing the latest news from all areas of the field, including its science, research, policy, and business.
Neuralstem Enters into Agreement with China Medical University in Taiwan to Develop Stem Cell Stroke Treatment
Neuralstem, Inc. announced recently that it has entered into a sponsored research agreement with the China Medical University & Hospital of Taiwan, in Taichung, Taiwan, to prepare for a human clinical trial using Neuralstem's human spinal cord neural stem cells to treat stroke patients.
GE Healthcare and Geron Announce Exclusive Global Agreement to Commercialize Stem Cell Drug Discovery Technologies
GE Healthcare and Geron Corporation recently announced that they have entered into a global exclusive license and alliance agreement to develop and commercialize cellular assay products derived from human embryonic stem cells for use in drug discovery, development and toxicity screening.
Ohio's Third Frontier Commission Awards $5 Million to Stem Cell Research
Ohio's Third Frontier Commission has awarded $5 million to a stem cell research center run by Case Western Reserve University, University Hospitals and Athersys.
StemCells, Inc. to be Added to Russell 3000 Index
StemCells, Inc. announced recently its expected addition to the Russell 3000(R) Index on June 26, 2009, when Russell Investments reconstitutes its comprehensive set of U.S. and global equity indexes.
Pluristem Therapeutics Was Awarded a $1.9 Million Grant From the Office of the Chief Scientist in the Israeli Government
Pluristem Therapeutics Inc. announced recently that the company was awarded a $1.9 million government grant from the Office of the Chief Scientist at the Ministry of Industry, Trade and Labor of Israel.
Novartis in Talks to Buy Much of Elan
Swiss drugmaker Novartis is in talks to buy parts of Irish peer Elan, including its flagship multiple sclerosis products and its Alzheimer's disease pipeline.
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POLICY
Senator Cardin Pledges to Fight for Biotech Funding
Some local life sciences players urged congressional leaders to significantly hike the amount of federal funding for small business research grants in testimony for a Senate committee hearing on whether the stimulus bill missed the boat with smaller biotechs.
State Panel Critical of California Stem Cell Institute
After an eight-month study, California's Little Hoover Commission yesterday released a 70-page report that said the stem cell institute's structure "is not adequate to protect taxpayers' interests or serve its own ambitious goals."
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