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TOP STORIES

Central Nervous System Repair? Neuronal Survival And Axonal Regrowth Obtained In Vitro
While repair of the central nervous system has long been considered impossible, French researchers from Inserm, the CNRS and the UPMC have just developed a strategy that could promote neuronal regeneration after injury. [Institut National de la Santé et de la Recherche Médicale, Montpellier]

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SCIENCE NEWS

New Tests Could Aid Early-Alzheimer's Diagnosis
Proteins in spinal fluid accurately detect early-stage Alzheimer's disease in patients and could pave the way for better drug research. [University of Gothenburg]

To Build a Human Brain
Markram is working to develop a model of the human brain because it is a key step to our understanding of the neo-cortex, and scientists cannot continue doing animal experimentation forever. [Ecole Polytechnique Federale de Lausanne, Lausanne]

Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.

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CURRENT PUBLICATIONS

Neural Stem Cells Improve Cognition via BDNF in a Transgenic Model of Alzheimer Disease
In this study, aged triple transgenic mice (3xTg-AD) that express pathogenic forms of amyloid precursor protein, presenilin, and tau were used to investigate the effect of neural stem cell transplantation on AD-related neuropathology and cognitive dysfunction. [Proceedings of the National Academy of Sciences]

Maintenance of Undifferentiated State and Self-Renewal of Embryonic Neural Stem Cells by Polycomb Protein Ring1B
This report addresses PcG regulation of stem cell self-renewal and differentiation through inactivation of Ring1B, a histone H2A E3 monoubiquitin ligase, in embryonic neural stem cells from the olfactory bulb of a conditional mouse mutant line. [Stem Cells]

Bcl11A/CTIP1 Regulates Expression of DCC and MAP1b in Control of Axon Branching and Dendrite Outgrowth
Here, the researchers report that Bcl11A/CTIP1/Evi9, a zinc finger transcription factor, downregulates axon branching. Knockdown of Bcl11A induced axon branching and multi-axon formation, as well as dendrite outgrowth. [Molecular and Cellular Neuroscience]

The Principal Neurons of the Medial Nucleus of the Trapezoid Body and NG2+ Glial Cells Receive Coordinated Excitatory Synaptic Input
This study reports that a defined type of glial cell in the medial nucleus of the trapezoid body receives excitatory glutamatergic synaptic input from the calyx of Held. [The Journal of General Physiology]



INDUSTRY NEWS

Connexon Creative Launches Cord Blood News
Cord Blood News is a weekly e-newsletter that keeps members of the cord blood community informed by providing the latest news from all areas of the field, including its science, research, policy, and business.

Junying Yu, Leading Stem Cell Researcher, Joins Cellular Dynamics International
Cellular Dynamics International announced today the appointment of Junying Yu, Ph.D., as senior research fellow. [Cellular Dynamics International, Madison]

Mesoblast to Apply For Regulatory Approval Of Its Bone Fracture Repair Products
Mesoblast Limited recently announced that it had commenced a formal process aimed at obtaining licenses from the Therapeutic Goods Administration to commercially manufacture and distribute its adult stem cell products in Australia. [Mesoblast, Melbourne]

Pennsylvania Researchers Win Fight Over Stem Cell Patent
Two University of Pittsburgh researchers won a patent ruling over their discovery that stem cells gleaned from liposuctioned fat could be used to produce bone, cartilage and muscle. [University of Pittsburgh, Pittsburgh]



POLICY NEWS

Maryland Slashes Stem Cell Budget by Another $3M in Plan to Trim $700M Budget Deficit
Maryland will cut its stem-cell budget for the fourth time in the past 15 months, as well as eliminate nine positions at its economic development agency, in the first phase of a cost-cutting plan approved Wednesday by Gov. Martin O'Malley.

Shake Up in Australian Stem Cell Research
As a part of the reshuffle, the ASSC has introduced four new foci for its efforts, called 'Collaborative Streams', which bundle together various research modules under an overarching theme.

Canadian Government Reviewing Loan-Program Request For Biotechs
The Canadian government is reviewing a proposal from an organization representing the country's biotech companies to help keep the industry afloat until the economy turns around.

Germany Tightens Law on Stem Cell Treatments
Treatments in Germany involving adult stem cells will be more closely regulated after revision of Germany's medical products law received final approval by the Bundesrat, the upper house of parliament.

Church Weighs in as Uruguay Debates Stem Cells
As Uruguayan Parliament considers going forward with embryonic stem cell research, the bishops of that nation are reiterating that an embryo is a human being with rights.



EVENTS

13th European Federation of Neurological Societies Congress
September 12-15, 2009
Florence, Italy

World Stem Cell Summit 2009
September 23-25, 2009
Baltimore, United States

Neuroscience 2009
October 17-21, 2009
Chicago, United States

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