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SCIENCE NEWS
Mayo Clinic Researchers Find Gene That Contributes to Two Different and Common Neurological Movement Disorders
Researchers have discovered that a single gene promotes development of essential tremor in some patients and Parkinson's disease in others. [Mayo Clinic, Jacksonville]
Gene Called 'Flower' Missing Link in Vesicle Uptake in Neurons
A channel that mediates an increase in calcium in the synapses has recently been identified in a series of experiments. [Baylor College of Medicine, Houston]
New Alzheimer's Genes Uncovered
The discovery of two new genes associated with Alzheimer's disease could provide valuable new leads in the race to find treatments and possibly cures for the devastating condition, according to a leading University scientist. [Cardiff University, Cardiff]
Polleux Lab Identifies Critical Gene for Brain Development and Mental Retardation
The Polleux lab discovered that establishing the neural wiring necessary to function normally depends on the ability of neurons to make finger-like projections of their membrane called filopodia. [University of North Carolina, Chapel Hill]
Function of a Neglected Structure in Neurons Revealed after 50 Years
Fifty years after it was originally discovered, scientists have elucidated the function of the endoplasmic reticulum found in neurons. [Friedrich Miescher Institute for Biomedical Research, Basel]
StemCells, Inc. Demonstrates Protection of Neurological Function in Batten Mouse
StemCells, Inc. recently announced the publication of preclinical data demonstrating for the first time that transplantation of its proprietary, purified human neural stem cells delays the loss of motor function in a mouse model of infantile neuronal ceroid lipofuscinosis. [StemCells, Inc., Palo Alto]
Human Brain Could Be Replicated In 10 Years, Researcher Predicts
A model that replicates the functions of the human brain is feasible in 10 years according to researchers. [Brain Mind Institute, Lausanne]
Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.
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CURRENT PUBLICATIONS
Chemokine CXC Receptor 4-mediated Glioma Tumor Tracking by Bone Marrow-derived Neural Progenitor/Stem Cells
In this study, the researchers isolated and characterized bone marrow-derived neural progenitor/stem cells, and show that CXCR4 is required for their chemotaxis and extracellular matrix invasion against a gradient of glioma soluble factors. [Molecular Cancer Therapeutics]
The DLK-1 Kinase Promotes mRNA Stability and Local Translation in C. elegans Synapses and Axon Regeneration
This paper shows that in C. elegans DLK-1 regulates not only proper synapse formation and axon morphology but also axon regeneration by influencing mRNA stability. [Cell]
Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis
Here the researchers purified non-genetically modified human CNS stem cells, grown as neurospheres (hCNS-SCns), transplanted into the brains of immunodeficient Ppt1/ mice where they engrafted robustly, migrated extensively, and produced sufficient levels of PPT1 to alter host neuropathology. [Cell Stem Cell]
Cdk4/CyclinD1 Overexpression in Neural Stem Cells Shortens G1, Delays Neurogenesis, and Promotes the Generation and Expansion of Basal Progenitors
To investigate whether G1 lengthening alone may cause the switch of cortical progenitors from proliferation to neurogenesis, the researchers manipulated the expression of cdk/cyclin complexes and found that cdk4/cyclinD1 overexpression prevents G1 lengthening without affecting cell growth, cleavage plane, or cell cycle synchrony with interkinetic nuclear migration. [Cell Stem Cell]
A Key Role for TRPM7 Channels in Anoxic Neuronal Death
Here, the researchers show that in neurons subjected to prolonged oxygen glucose deprivation, antiexcitotoxic therapy unmasks a dominant death mechanism perpetuated by a Ca2+-permeable nonselective cation conductance. [Cell]
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INDUSTRY NEWS
Connexon Creative Launches Mesenchymal Cell News
Mesenchymal Cell News is a free, weekly e-newsletter that keeps the mesenchymal cell community informed by providing the latest news from all areas of the field, including its science, policy, and business.
BrainStorm Cell Therapeutics Enters into Agreement for Clinical-Grade Stem Cell Production for ALS
BrainStorm Cell Therapeutics Inc. announced recently that it has entered into an agreement with Protein Production Services Ltd. to start Good Manufacturing Practice production of its stem cell therapeutic product. [BrainStorm Cell Therapeutics, Petach Tikvah]
University of Missouri Licensing Revenue Hits $10 Million
The University of Missouri's technology transfer program topped $10 million in licensing income for the first time ever. [University of Missouri, St.Louis]
Biotech Startup Hopes Light-activated Nerve Cells will Make it a Northeast Ohio Star
LucCell Inc.'s light switches, which sprang from research at Case Western Reserve University, allow neurons silenced by a spinal cord injury or brain cells malfunctioning due to disease might someday resume working when triggered by flashes of laser light. [LucCell Inc., Cleveland]
Californian Budget Deficit Poses "Real Risk" to Biotech Investment
Biotech has played a large role in shaping California over the past 30 years but the new financial frugality has created a difficult relationship between the industry and the state.
United States Patent and Trademark Office Publishes Stemedica's Patent Application for the Treatment of Diabetic Retinopathy
Stemedica Cell Technologies, Inc. has filed a patent application for the use of multiple stem cells and a transplantation methodology in the treatment of Diabetic Retinopathy. [Stemedica Cell Technologies, Inc., San Diego]
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POLICY NEWS
Safety Call Over Stem Cell Trips
A clampdown on unproven and potentially unsafe stem cell research is being called for by an expert group.
How Will Science Fare?
This year, there is a new twist in the Japanese education ministry's budget requests: The newly elected Democratic Party now has responsibility for finalizing the budget, and no one knows how R&D will fare.
Ethics Scrutiny Needed for Chinese-European Projects
Biomedical research collaborations between Europe and China need greater ethical oversight to combat unregulated stem-cell therapies and prevent the exploitation of clinical-trial participants according to experts.
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EVENTS
World Stem Cell Summit 2009
September 23-25, 2009
Baltimore, United States
TERMIS 2nd World Congress 2009
August 31 - September 3, 2009
Seoul, South Korea
The 2nd Annual Maryland Stem Cell Research Symposium
September 21 2009
Baltimore, United States
Neuroscience 2009
October 17-21, 2009
Chicago, United States
Alzheimer's Disease Beyond Abeta
January 10-15, 2010
Copper Mountain, United States
Molecular Medicine Tri-Conference 2010
February 3-5, 2010
San Francisco, United States
ISSCR 8th Annual Meeting
June 16-19, 2010
San Francisco, United States
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